No Link Between Testosterone Levels and Risk for Prostate Cancer

In what is the most definitive research report to date, a study in the February 6, 2008, issue of the Journal of the National Cancer Institute "confirms the lack of evidence to support an androgen[testosterone]-prostate cancer hypothesis," according to an accompanying editorial.

This conclusion comes from a huge pooled analysis of data from 18 studies consisting of 3,886 men with prostate cancer and 6,438 controls. Each of the studies had looked at the relationship between testosterone levels, free testosterone, dihydrotestosterone (DHT), dehydroepiandrosterone sulfate (DHEA-S), androstenedione, androstanediol glucuronide, estradiol and calculated free estradiol, and the risk for prostate cancer. They found no significant relationship between the serum levels of any of these hormones and the risk of developing prostate cancer.

Prostate cancer is the second leading cancer in men. Because testosterone is required for growth and development of the prostate gland, and prostate tumors respond to androgen deprivation therapy, high androgen levels had been hypothesized as possible risk factors. This study effectively puts this concern to rest. This frees standard medicine to move forward with decreasing heart attack deaths, diabetes and cholesterol by optimizing testosterone with the natural hormones—as Holistic physicians have been doing for decades.

For more information, see "Testosterone Therapy."

Reference:

J Natl Cancer Inst. Published online January 29, 2008. 2008;100:158-159, 170-183.

Click here for more information on this study (free registration required).